An encouraging progress report on the treatment of progeria and its implications for atherogenesis.
نویسندگان
چکیده
Department t o o of f f Pa Pa Path th thol ol o og og ogy y
منابع مشابه
A Case Report of Hutchinson-Gilford Progeria Syndrome
Hutchinson-Gilford Progeria Syndrome (HGPS), a rare genetic condition occurs one in every 8 million live births. HGPS is characterized by premature aging in various organs. The average survival rate of the affected patients is 13 years, and their most common causes of death are myocardial infarction and stroke. This disease occurs due to a gene mutation in the chromosomes of the patient. There ...
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Hutchinson-Gilford progeria syndrome is an extremely rare condition with features of premature and accelerated aging. The pattern of inheritance is unclear, although autosomal dominant mutations have been proposed. The disease presentation is usually in infancy and early childhood with a characteristic phenotype of short stature, abnormal skin and nail, beaked nose, loss of subcutaneous f...
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The affinity of low density lipoprotein(LDL) to its receptor is very important, because most of LDL-uptake pathway is done by the LDL receptor and the change in size of LDL particle and the modification in its components may affect the LDL affinity for its receptor. In this study, the effects of a powerful lipid-soluble antioxidant “ubiquinol-10” have been investigated on the affinity of LDL to...
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عنوان ژورنال:
- Circulation
دوره 130 1 شماره
صفحات -
تاریخ انتشار 2014